| Sonntag 17. September 2017 | |||||
| 20:00 | Córdoba |  | 2 - 0 |  | CD Teneriffa |
| 18:00 | Real Oviedo |  | 1 - 0 |  | Cádiz |
| 18:00 | Gimnàstic Tarragona |  | 3 - 1 |  | Albacete Balompie |
| 16:00 | Alcorcón |  | 1 - 1 |  | Barcelona II |
| 12:00 | Cultural Leonesa |  | 3 - 2 |  | Huesca |
| Sonnabend 16. September 2017 | |||||
| 20:30 | Numancia |  | 3 - 0 |  | Sporting Gijón |
| 20:00 | CA Osasuna |  | 2 - 1 |  | Almería |
| 18:00 | Sevilla II |  | 0 - 0 |  | Rayo Vallecano |
| 18:00 | Lorca |  | 1 - 1 |  | Reus Deportiu |
| 16:00 | Real Valladolid |  | 2 - 1 |  | FC Granada |
| Freitag 15. September 2017 | |||||
| 21:00 | Lugo |  | 2 - 1 |  | Real Saragossa |
